KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKDC
All Species:
25.76
Human Site:
Y2299
Identified Species:
62.96
UniProt:
P78527
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78527
NP_001075109.1
4128
469089
Y2299
C
G
I
Q
S
S
E
Y
F
Q
A
L
V
N
N
Chimpanzee
Pan troglodytes
XP_001147162
4128
468882
Y2299
C
G
I
Q
S
S
E
Y
F
Q
A
L
V
N
N
Rhesus Macaque
Macaca mulatta
XP_001100610
4128
469402
Y2299
C
G
I
Q
S
S
E
Y
F
Q
A
L
V
N
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97313
4128
471369
Y2295
C
D
I
T
S
A
M
Y
F
E
A
L
V
N
N
Rat
Rattus norvegicus
NP_001101797
2098
241314
E433
R
E
Q
Q
H
I
M
E
E
L
F
Q
T
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514950
4153
474137
Y2321
C
G
I
D
S
A
R
Y
F
Q
A
L
A
N
N
Chicken
Gallus gallus
Q8QGX4
4134
472639
Y2298
C
E
I
D
R
V
R
Y
F
Q
A
L
V
S
N
Frog
Xenopus laevis
Q9DEI1
4146
473487
Y2319
C
G
I
D
P
E
R
Y
F
Q
S
L
A
N
N
Zebra Danio
Brachydanio rerio
XP_001919588
4119
467204
Y2305
C
G
I
E
H
D
R
Y
F
Q
S
L
A
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781813
1817
205237
Q152
Q
P
K
T
E
C
L
Q
I
I
T
A
R
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.5
N.A.
N.A.
79.1
39.2
N.A.
74.1
68.8
64
58.5
N.A.
N.A.
N.A.
N.A.
20.8
Protein Similarity:
100
99.8
98.8
N.A.
N.A.
88.7
44.7
N.A.
85.4
82.5
79.8
76.1
N.A.
N.A.
N.A.
N.A.
31.6
P-Site Identity:
100
100
100
N.A.
N.A.
66.6
6.6
N.A.
73.3
60
60
60
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
N.A.
N.A.
80
6.6
N.A.
80
66.6
66.6
73.3
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
20
0
0
0
0
60
10
30
0
0
% A
% Cys:
80
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
30
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
20
0
10
10
10
30
10
10
10
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
80
0
10
0
0
0
10
% F
% Gly:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
80
0
0
10
0
0
10
10
0
0
0
10
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
0
0
10
0
80
0
0
0
% L
% Met:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
80
% N
% Pro:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
10
40
0
0
0
10
0
70
0
10
0
0
0
% Q
% Arg:
10
0
0
0
10
0
40
0
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
0
50
30
0
0
0
0
20
0
0
10
0
% S
% Thr:
0
0
0
20
0
0
0
0
0
0
10
0
10
10
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
50
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _